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Most popular food recipes use a combination of salt and sugar, which might be good for our blood pressure and overall health, but not necessarily the health of our waistline. In fact, according to the CDC's most recent dietary guidelines, many sweeteners have been linked to diabetes or increased risk of metabolic syndrome. Aspartame is one such culprit — it contains phenylalanine that interferes with the synthesis of tyrosine in the brain. If you use aspartame with other foods that contain phenylalanine (such as chocolate), it could cause hyperactivity in children with ADHD.

Acesulfame potassium, the artificial sweetener known as Sunett, is 200 times sweeter than sugar and contains zero calories. It's made from acetoacetic acid (which is derived from acetone) and a methyl ester bond. The FDA has found that prolonged exposure to mixtures of carbonyl compounds like acesulfame potassium can cause cancer in lab animals. It also increases insulin levels, which may contribute to diabetes. Despite these discoveries, the FDA has approved acesulfame potassium for consumption — even though there are safer alternatives.

Sucralose, sold under the brand name Splenda, is 600 times sweeter than sugar. The FDA has received more than 24,000 consumer complaints about Splenda, including reports of severe migraines and memory loss. In addition to aspartame and sucralose, this list also includes saccharin, which was first discovered in 1879. For a long time, it was believed to be harmless — but that belief began to change in the 1980s when researchers found that saccharin caused bladder cancer in rats. More recent studies have also linked it to tumors, reproductive problems and glucose intolerance.

Since aspartame contains phenylalanine, you might wonder whether there are any substitutions available. In fact, Dean Ornish has a good recipe for aspartame-free ketchup on his website. He recommends using Splenda to make it — you can buy it in a bulk package — or you could even try agave nectar. Agave syrup is made from the sap of the agave plant and is used as an alternative sweetener because it's digested slowly and doesn't raise blood glucose levels as much as sucrose. This makes it perfect for diabetics, but also good for anyone who would like to lose weight or lower their blood sugar.

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